First contemporary case of human infection with Cryptococcus gattii in Puget Sound: evidence for spread of the Vancouver Island outbreak.
نویسندگان
چکیده
We report a case of cryptococcosis due to C. gattii which appears to have been acquired in the Puget Sound region, Washington State. Genotyping confirmed identity to the predominant Vancouver Island genotype. This is the first documented case of human disease by the major Vancouver Island emergence strain acquired within the United States.
منابع مشابه
Molecular evidence that the range of the Vancouver Island outbreak of Cryptococcus gattii infection has expanded into the Pacific Northwest in the United States.
Cryptococcus neoformans frequently causes fungal meningitis in immunocompromised patients, whereas the related species C. gattii is restricted to tropical and subtropical regions,where it usually infects immunocompetent individuals.An outbreak of C. gattii infection that began in 1999 on Vancouver Island has resulted in endemic C. gattii infection and caused numerous human and veterinary infect...
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During 1999, the eastern portion of Vancouver Island, British Columbia began experiencing an outbreak of a rare cryptococcal disease previously known to exist only in tropical and sub-tropical regions. It is thought that this outbreak on Vancouver Island is the world’s largest outbreak of cryptococcosis ever identified. It is not yet understood how this pathogen, widely regarded as a “tropical”...
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Cryptococcus gattii, the sister species of Cryptococcus neoformans, is an emerging pathogen which gained importance in connection with the ongoing cryptococcosis outbreak on Vancouver Island. Many molecular studies have divided this species into for major lineages: VGI, VGII, VGIII, and VGIV. This commentary summarizes the whole-genome sequencing (WGS) studies that have been carried out with th...
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1. Datta K, Bartlett KH, Baer R, Byrnes E, Galanis E, Heitman J, et al. Spread of Cryptococcus gattii into Pacific Northwest region of the United States. Emerg Infect Dis. 2009;15:1185–91. http://dx.doi. org/10.3201/eid1508.081384 2. Brandt ME, Hutwagner LC, Klug LA, Baughman WS, Rimland D, Graviss EA, et al. Molecular subtype distribution of Cryptococcus neoformans in four areas of the United ...
متن کاملCryptococcus gattii Genotype VGIIa Infection in Man, Japan, 2007
We report a patient in Japan infected with Cryptococcus gattii genotype VGIIa who had no recent history of travel to disease-endemic areas. This strain was identical to the Vancouver Island outbreak strain R265. Our results suggest that this virulent strain has spread to regions outside North America.
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 45 9 شماره
صفحات -
تاریخ انتشار 2007